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Depressive symptoms and chronic obstructive pulmonary disease: effect on mortality, hospital readmission, symptom burden, functional status, and quality of life

Hypoxia, a common feature of the TME, can further increase VEGF expression by activating hypoxia-inducible factor 1-alpha (HIF-1), a transcription factor that plays a critical role in the cellular response to low oxygen levels

- Favorece a oxidao das gorduras, proporcionando mais energia e melhora da composio corporal