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Each compound clears a different bottleneck at the same dermal target: Collagen quality and firmness GHK-Cu activates collagen-gene transcription and supplies the copper cofactor for cross-linking Microvascular delivery BPC-157 builds the capillary network that feeds active tissue Organized tissue, scar remodeling full-length TB-4 mobilizes repair cells with anti-scarring bias Inflammation control KPV pre-empts NF-B-driven flushing, redness, and reactive flares Practical readouts: hydration and texture by 24 weeks, fine lines softening by 48, firmer structure and scar remodeling by 812

Reviews in endocrine & metabolic disorders, 15(3), 181187.