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Description

[PubMed: 17717290] 671

Additional physiological functions have been identified by means of GLP-1 agonists such as exenatide (exendin-4

These findings propose that exendin4 could attenuate breast cancer cell proliferation by inhibiting the NF B activation which reduces the expression of its target genes [84]

Tirzepatide has since become a foundational reference compound in incretin pharmacology, with hundreds of peer-reviewed publications characterising its receptor binding kinetics, biased signalling profile, and downstream effects across pancreatic, hepatic, adipose, and central nervous system tissues