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Statistical analysis Statistical analyzes were conducted using GraphPad Prism 9.5.1 (GraphPad Software Inc., San Diego, CA, USA)

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Clinical trials in people with type 2 diabetes and CKD have shown potential kidney benefits with semaglutide, though this is not a licensed renal indication in the UK

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Control rats exhibited preserved ultrastructural integrity, characterized by axonal terminals with intact membranes without swelling, mitochondria displaying organized cristae and intact membranes (Fig

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