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In addition, TLR2 inhibition has been reported to reduce SLE-associated symptoms further indicating that hyperresponsiveness to gut bacteria is likely to contribute to disease pathogenesis (Pawar et al

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This decision followed careful analysis and clinical trials assessing its efficacy and safety for adult patients with obesity

FIGURE 4 The future perspectives outlined above can contribute to advancing our understanding of the role of -blockers in modulating metabolic parameters and oxidative stress, ultimately guiding the development of more effective and personalized therapeutic strategies for patients with metabolic disorders and cardiovascular diseases