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6e, all three GSSG-enhancing chemicals increased the levels of IKK--SSG adducts, suggesting that GSSG accumulation restrained IKK- activity by promoting IKK- S -glutathionylation, leading to subsequent NF-B suppression

Serum folate reflects short-term changes in diet and may be altered by recent meals, so fasting for about six hours beforehand is required, and repeated testing is needed to identify true deficiency

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CD19 + CD38 + Akt + B cells one - way ANOVA p = 0.0023, Sidaks post-hoc test p values corrected for multiple comparisons: B6.TC (Veh) vs B6.TC/Rab4A Q72L (Veh) p = 0.0027, B6.TC/Rab4A Q72L (Veh) vs B6.TC/Rab4A Q72L (NAC) p = 0.0018, B6.TC/Rab4A Q72L (Veh) vs B6.TC/Rab4A Q72L (Rapa) p = 0.0187, B6.TC/Rab4A Q72L (Veh) vs B6.TC/Rab4A Q72L -KO (Veh) p = 0.0031