When to seek medical advice : Patients should contact their GP, diabetes specialist nurse, or NHS 111 urgently if they experience: Severe, persistent abdominal pain, especially if radiating to the back (possible pancreatitis) Persistent vomiting (unable to keep down fluids for more than 24 hours) Signs of dehydration (extreme thirst, dry mouth, reduced urination, dizziness) Fever, jaundice, or right upper abdominal pain (possible gallbladder disease) If nausea significantly impacts their ability to maintain adequate nutrition These symptoms may warrant dose reduction, temporary treatment interruption, or switching to an alternative GLP-1 preparation with a potentially better tolerability profile
B12 deficiency can develop gradually and may present with a range of symptoms, some of which overlap with other conditions
What they did: Systematic characterization of a family of synthetic melanocortin peptides
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