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The goal is finding the minimum effective dose, not automatically climbing to the maximum

Dehydration amplifies side effects like nausea, fatigue, and constipation

This dual mechanism explains why some patients report feeling intoxicated faster or experiencing more pronounced symptoms

I still believe there is an increased risk, it's just not as high as we thought from the early investigations done with these medications." Khan also avoids writing prescriptions when people have a family history of medullary thyroid cancer because for many years, there has been a described association between GLP-1 medications and thyroid cancer, he says