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Expected Volatility Due to the Companys limited operating history and lack of company-specific historical volatility as a public company, due to the Company's IPO in October 2024, or implied volatility as a private company, the expected volatility was estimated based on the average volatility for comparable publicly traded biopharmaceutical companies over a period, where available, equal to the expected term of the stock option grants

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The median survival duration is 11 months, with a five-year survival rate of 6.8% [23], which is lower than in sporadic MPNST [23,24]