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Cell-based studies suggest that Gly-related regulation is more often reflected in its effects on reducing capacity and the stress threshold: by influencing GSH supply and ROS stress, Gly may indirectly alter the extent of pro-inflammatory signaling amplification and phenotypic stability (66)

SNP-affected probes were filtered using the recommended annotations described by Zhou et al., and multi-hit/cross-reactive probes were removed based on published lists implemented in ChAMP (e.g., Nordlund et al.)

They include genetics, ageing, and lifestyle elements like insufficient sleep, stress, and poor nutrition