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Glutathione depletion induces ferroptosis, autophagy, and premature cell senescence in retinal pigment epithelial cells

The CBB-stained gel was digitally imaged (GelDoc, Bio-Rad, USA) under UV excitation, and the image was analyzed with the software PDQuest 2D Elite

Notably, no significant increases in markers of inflammation or oxidative stress were observed in the liver of Gclc L-KO mice compared to Gclc WT mice (Fig