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Lower abdominal pain in women can have a range of causes, from mild issues to serious, life-threatening conditions

Our multidisciplinary approach ensures that underlying contributors to hemorrhoid development, such as constipation or dietary factors, are addressed alongside the surgical intervention to minimize recurrence risk and promote long-term relief

Interestingly, prediction of SUMO-interaction motifs and SUMOylation sites in SnCE1 suggests SnCE1 might be SUMOylated and interacting with SUMO (Supplementary Table 2)

If a second primary antibody was used, the cells were incubated either for 2 h at room temperature or overnight at 4C