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With all the expanding possible indications, the GLP-1 peptides are being prescribed off-label for many purposes, and now people are microdosing the drugs despite the lack of data

Long-Term Safety Considerations While 24-week human trials provide reassurance about short-to-medium term safety, very long-term data (multi-year continuous use) is limited

Interestingly, coeliac patients also display heightened production of RF at mucosal sites in their GI tract, specifically the jejunum, implying that the immunogenic response generated subsequent to gluten exposure may contribute towards RF synthesis and downstream RA pathogenesis (Hllgren et al

The result: GLP-1 and amylin both slow gastric emptying, but through different signaling