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Finally, although the correlations between the metabolome and microbiome were established using robust statistical analyses, there was limited statistical power and there are also limitations to the statistical approaches used herein (e.g., log transformation to resolve non-normal distribution and/or heteroscedasticity 103 )

Such approaches enhance the understanding of structure-function relationships across the broader peptide family

Antioxidant Gene Expression and Oxidative Stress Pathways The AEDG sequence has also been investigated for its effects on oxidative stress response pathways a research domain that intersects with its pineal and telomere-related activities, since oxidative damage is both a driver of telomere attrition and a consequence of melatonin decline