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The composition according to any one of the preceding embodiments, wherein the composition comprises an isotonic agent being present in a concentration from 8 mg/ml_ to 50 mg/ml_, such as 14 mg/ml_ to 30 mg/ml_ of the composition
L'activation des neurones MC4R du noyau paraventriculaire inhibe les signaux orexigenes du systeme agouti-related peptide (AgRP) et stimule les signaux anorexigenes de la pro-opiomelanocortine (POMC)
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