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Environment: Irritants in the surrounding environment can trigger allergic reactions leading to eczema

Cells were incubated with appropriate secondary antibody conjugated with DyLight-488 or 650 (Invitrogen) for 1 hour

These include systemic symptoms, such as fatigue, a deteriorated mood, and muscle and joint pain (246, 247)

Together, these results suggest that sleep and sleep deprivation bi-directionally can impact the molecular signalling pathways that regulate synaptic strength and control brain plasticity, supporting the hypothesis of a direct relation between cortical plasticity and sleep regulation ( Figure 4 )