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J Pharm Pharmacol 74:573584 Althagafy HS, El-Aziz MKA, Ibrahim IM, Abd-Alhameed EK, Hassanein EHM (2023) Pharmacological updates of nifuroxazide: promising preclinical effects and the underlying molecular mechanisms

Furthermore, the presence of circulating mature endothelial cells, endothelial progenitor cells, and endothelial microparticles is taken into account (64)

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But based on the published data, I do not think one can reasonably claim that retatrutide is muscle sparing