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Where most therapeutic peptides degrade within minutes under simulated gastric or intestinal conditions, BPC-157 retains its integrity in human gastric juice for more than 24 hours, tolerates a wide pH range, and resists multiple proteolytic enzymes including pepsin and trypsin

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Next, we detail several mechanistic links by which the microbiome can trigger or protect against neurodegeneration spanning immune modulation, metabolic and neuroendocrine signaling, microbial neurotransmitter production, and effects on protein aggregation and epigenetic regulation