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Circ Res 90:966973 Carmeliet P, Ferreira V, Breier G, Pollefeyt S, Kieckens L, Gertsenstein M, Fahrig M, Vandenhoeck A, Harpal K, Eberhardt C et al (1996) Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele

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Nobiletin, a citrus flavonoid, inhibits hepatic lipid accumulation and decelerates the progression of NAFLD by regulating M1/M2 macrophage polarization through enhanced autophagy and by suppressing the NLRP3 inflammasome, a critical contributor to inflammatory cell death (210)