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Unknown Long-Term Effects : The compound lacks approved human clinical trial data, meaning long-term safety remains entirely undocumented

In support of the idea that cross-protective immunity exists, recent HCoV infections were found to be associated with less severe COVID-19 upon infection with ancestral SARS-CoV-2 [103], and infection with SARS-CoV-2 of any variant was also associated with a reduced incidence of subsequent HCoV infection

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