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The presence of positive internal controls (inflammatory or endothelial cells) was strictly required to assess the immunohistochemical signal

Combination therapies: Orforglipron could be combined with other oral agents (e.g., oral GIP agonists, SGLT-2 inhibitors, phentermine) for enhanced efficacy, or formulated as a fixed-dose combination tablet

The overall mean values for G6PD activity have to be optimized in individual laboratories to determine the cut-off points for moderate and severe G6PD deficiency

One promising strategy is to increase the concentration of antioxidants (e.g., vitamin E, glutathione, etc.) in the lung, particularly at the surface of the respiratory epithelium, to counteract air pollution-induced oxidative stress