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As primarily secreted proteins, IGFBPs are released into the extracellular space, where they interact with IGF-1 (Oxvig and Conover, 2023)

Acetanilide was used as an internal standard and added to the sample before solid phase extraction (SPE) at a concentration of 100 M

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Increase your fluid intake: Hypovolemia, or lower levels of blood volume, may be helped, in part, by increasing the amount of water or electrolyte sports drink that you consume.[ref] Increased sodium intake: Similar to increasing fluid intake, if your sodium intake is low or your electrolyte balance is off, it can affect blood volume.[ref] Often, people with POTS are encouraged to drink sports drinks such as Gatorade