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Description

This scoping review investigates the biological rationale and evidence for the use of glucagon-like peptide-1 receptor agonists (GLP-1RAs) in PsD

GLP-1S binds with high affinity to the GLP-1 receptor (GLP-1R, a class B G-protein-coupled receptor) and acts as an agonist in preclinical models

6 Toxicity and safety Research into the acute toxicity of GPS in animal models, including mice and rats, indicates that GPS exhibits a relatively low level of acute toxicity

The combination of physical exertion, heat, and pre-existing risk factors produces an event rate substantially higher than the general population