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Some people experience mild digestive discomfort, bloating, or nausea, especially when taking it on a completely empty stomach

Epicardial adipose tissue may mediate deleterious effects of obesity and inflammation on the myocardium

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According to Belle Health safety information, these medications are contraindicated for individuals with: Personal or family history of medullary thyroid carcinoma Multiple endocrine neoplasia syndrome type 2 (MEN2) History of pancreatitis Known hypersensitivity to tirzepatide or any of its components Additionally, women who are pregnant, planning to become pregnant, or breastfeeding should not use tirzepatide