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While intermediate metabolites associated with TCA cycle (Tricarboxylic Acid Cycle) such as fumarate, succinate, and malate were not significantly different between the groups, we suggest a decrease in mitochondrial activity may result in lower ATP generation as reported in other inflammatory conditions (65, 66)

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For instance, LPS, a material well-known for its ability to induce inflammatory responses, did not promote modulation of the different cytokines/chemokines at 30min/day exposure (Table 4)