oral semaglutide efficacy and safety of monotherapy vs placebo in a predominantly Chinese population with type 2 diabetes (PIONEER 11): a double-blind, Phase IIIa, randomised trial First Time: Orally Available GLP-1

This medication is the first drug treatment to be FDA-approved for weight management since 2014

Study of Dry Eye Syndrome: Focus on Causative Factors, Treatment Modalities, Quality of Life, and Preservatives Used in Eye Drops

Although the physiological effects of this naturally occurring molecule are short-lived due to its rapid degradation by the enzyme DPP-4, the wide variability of therapeutic benefits motivated the synthesis of GLP-1RAs

For pathway reconstitution experiments, the codon-optimized BCCT gene (Aci1347) was cloned into plasmid pGEX-6P-1- cntAB using the In-Fusion cloning system (Takara) yielding construct pGEX-6P-1- cntAB-bcct