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Unlike medication effects, which are usually aimed at altering action of one receptor or enzyme to ameliorate psychiatric symptoms [e.g., serotonergic pathway, glutamatergic pathway (108)], the low glutamate diet aims to reduce glutamatergic excitotoxicity while concurrently increasing consumption of nutrients known to be protective against excitotoxicity, with the aim of improving neurotransmission (69, 109)

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Although the drug is effective, less sensitive strains are emerging

The ethanol-induced cytochrome P450 present in the MEOS was purified and designated as CYP2E1