Its use is limited to analytical investigation, receptor-mediated signaling studies, and cellular pathway modeling conducted under structured experimental protocols
In all models, the following fixed covariates were entered: assigned treatment (investigational product or placebo), baseline measurement of the outcome of interest, visit (day 14 1 day or day 28 1 day), visit in interaction with treatment, period (period 1 or period 2), sex and, for MIDT outcomes, incentive level
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