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Typically, candidates for tirzepatide for weight loss include: Adults with a body mass index (BMI) of 30 kg/m or greater (classified as obesity) Adults with a BMI of 27 kg/m or greater who also have at least one weight-related health condition, such as type 2 diabetes, high blood pressure, or high cholesterol Tirzepatide is not intended for individuals with a personal or family history of medullary thyroid carcinoma, those with multiple endocrine neoplasia syndrome type 2, or anyone with a known hypersensitivity to the medication