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In Crohn's disease, this dual mechanism can affect symptom presentation unpredictablysome patients experience reduced inflammation, while others report increased cramping or diarrhea depending on disease location and baseline gut permeability

To maintain increased antioxidant levels, it is important to take care of diet and exercise and avoid the factors which are detrimental to skin health like smoking, alcohol, and lack of sleep discipline

[1] [2] Older patients may be more susceptible to dehydration from vomiting or diarrhoea and require closer monitoring