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There is no definitive evidence supporting probiotics, digestive enzymes, or most other supplements specifically for GLP-1 nausea, though individual patients may report subjective benefit

A 2023 analysis of 340 patients using semaglutide with 16:8 fasting (16-hour fast, 8-hour eating window) found that medication users achieved their fasting goals on 2.3 days per week more consistently than fasting-only controls

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Its subject to a progressive decline in elasticity, smoothness, and even skin tone as a consequence