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The distinct contributions of each receptor system - GLP-1-mediated improvements in insulin sensitivity and appetite regulation, GIP-mediated enhancement of insulin secretion and adipose tissue function, and glucagon-mediated direct hepatic metabolic modulation and increased energy expenditure - create synergistic benefits when engaged through dual or triple agonist formulations
Normalization of fasting hyperglycaemia by exogenous glucagon-like peptide 1 (7-36 amide) in type 2 (non-insulin-dependent) diabetic patients
2017;1862(10 Pt B):116677
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