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Injections are subcutaneous (under the skin), typically into the abdomen, thigh, or upper arm, and injection sites should be rotated weekly to prevent tissue buildup at any one spot

More recently, a Because tirzepatide is both a Still, its important to keep in mind that there are limitations to these studies, and more long-term research is needed before determining that one medication is more effective than another

Finally, another layer of complexity is added when considering the evidence of a leaky bloodbrain barrier across several neuropsychiatric disorders 255 , which could further increase the brain penetrance of GLP-1RAs administered to people with such illnesses