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DMSO is itself a known skin irritant and penetration enhancer, so community sources often attribute these reactions to the carrier as much as to Dihexa

The results reported that both doses of Dihexa increased levels of AngIV in the brains of APP/PS1 mice, with the 2.88 mg/kg dose increasing these levels to almost the same amount in the wild type

In addition, some drugs, such as rosiglitazone and GW9662, the peroxisome proliferator-activated receptor gamma (PPAR) agonist and antagonist, respectively, also regulate cell proliferation through the HGF/c-Met axis

A vial that might have been stable for weeks in a controlled, refrigerated environment could see its bacteriostatic properties plummet in a matter of days if left on a lab bench, especially one that gets sunlight