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This decision must be made collaboratively with a prescribing clinician, considering individual response, adverse effects, and treatment goals

Warnings and Contraindications A personal or family history of medullary thyroid cancer Gastroparesis Multiple endocrine neoplasia type 2 Type 1 diabetes The Takeaway The FDA has granted accelerated approval for GLP-1 receptor agonist drug semaglutide as a first-line treatment for adults with moderate to severe MASH

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Compounders have argued their products are legal under a narrow provision of federal law that allows compounding when patients require personalisation due to medical concerns, like the addition of vitamins or doses not available in the branded versions