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Scientific References Metformin and reduced vitamin B12 levels: new advice for monitoring patients at risk

To enhance interpretability despite this variability, we pooled outcomes within instruments (HDRS, BDI, MADRS), conducted prespecified subgroup analyses by comparator group and age, used random-effects models, performed leave-one-out sensitivity analyses and publication-bias diagnostics, and applied meta-regression to examine treatment duration and daily dose

Clear signal, not panic: two large cohorts just tied GLP-1s (semaglutide/tirzepatide) to eye outcomes

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