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Given the limited evidence base, patients should weigh the financial commitment against the uncertain benefits and prioritise proven interventions first

Previous AngIV analogs, while showing promise in animal models of dementia, were hindered by poor metabolic stability indicated by a short half-life, and an inability to cross the BBB due to their peptide nature

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Nevertheless, Ozempic carries a warning about this potential risk, and its use is generally contraindicated in individuals with a personal or family history of MTC or in those with Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)