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It is also possible that while heating is effective at disrupting protein shapes and eliminating enzyme activity, it does not eliminate ice nucleation activity as the proteins are twisted into new shapes that have ice nucleation sites, similar to the hypothesis that defects and aggregation of large proteins are a source of ice nucleation sites 55

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After intramuscular and intravenous administration of Tritium-labeled BPC-157, the elimination half-life of BPC-157 was less than 30 minutes