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The medication is administered as a once-weekly subcutaneous injection and is intended to be used alongside a reduced-calorie diet and increased physical activity

While this is helpful, it may not always be enough to keep the weight off long-term

10.1038/s41575-021-00440-6 31 Sanchez-RodriguezE.Egea-ZorrillaA.Plaza-DiazJ.Aragon-VelaJ.Munoz-QuezadaS.Tercedor-SanchezL.et al (2020)

Genetic Predispositions in Glutathione Metabolism and Detoxification Variations in genes encoding glutathione S-transferase isoforms, gamma-glutamyl synthetase, and glutathione reductase influence individual glutathione synthesis, recycling, and detoxification capacity