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And that is, we can use a medication very helpful and the food cravings go down, the food noise goes down, I'm not struggling, I don't have to count calories every day

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Every one of these mechanistic claims, however, rests on animal and in-vitro data there is no human mechanistic confirmation

GLP1R agonists increase heart rate and might not be beneficial in individuals with severe left ventricular dysfunction, reduced ejection fraction and/or a history of repeated hospitalization for heart failure