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The results also showed that metformin may reduce the risk factors for coronary heart disease , including high fasting insulin , leptin , and low-density lipoprotein (bad) cholesterol

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L-glutamine, which helps generate glutathione

5 Future directions The potential of GLP-1RAs as dual-action therapies, targeting both metabolic dysfunction and immune dysregulation, makes them particularly compelling candidates for early PsA, where intervention may alter disease trajectory