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Apmis 123 , 697705 (2015)

The ratio of GSH and GSSG within cells is a measure of cellular oxidative stress, where an increase in GSSG to GSH ratio is indicative of greater oxidative stress

Compared to cAMP accumulation, all three agonists had transduction coefficients that were significantly lower for IP 1 , pAKT, pERK and pCREB, suggesting that these agonists favored cAMP signaling over all other pathways tested (Figure 1F

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