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Patients should not discontinue metformin due to concerns about neuropathy without consulting their healthcare provider, as the benefits of glycemic control typically outweigh the manageable risk of B12 deficiency

10.1056/NEJMoa2032183 67 WitkowskiM.WilkinsonL.WebbN.WeidsA.GlahD.VrazicH

Regardless the importance of GST activity for cellular vitality and health, the GST gene cluster is a hotspot for DNA sequence mutations that leads to the expression of active but functionally different GST variant proteins

Do not use Saxenda if: you or any of your family have a history of MTC you have MEN 2