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We need to look at the organelles, the precise compartments, to understand how metabolites influence human health.

14 It is characterized by an irreversible decline in physiological function, leading to increased susceptibility to chronic diseases and reduced resilience to stress

Animal and in vitro studies have reported a wide range of Mn-induced pulmonary effects, including lung damage, inflammation, alveolar macrophage infiltration, and oxidative stress (Gandhi et al., 2022)

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