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Evidence: Investigational mainly animal and cell data

Kim C, Lee SG, Yang WM, Arfuso F, Um JY, Kumar AP, et al

Furthermore, studies performed in endothelial cells, Kaposis sarcoma-associated herpesvirus (KSHV)-transformed cancer cells and several normal fibroblast or epithelial cell lines reported a similar effect of asparagine on supporting cell survival and protein translation after glutamine deprivation 44,49,50

Many patients prescribed Ozempic are already taking metformin, which is commonly used as first-line therapy for type 2 diabetes according to NICE guidelines (although SGLT2 inhibitors may be first-line in certain cardio-renal risk groups)