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Ann Oncol 23:748753 Stocker G, Hacker UT, Fiteni F et al (2018) Clinical consequences of chemotherapy dose reduction in obese patients with stage III colon cancer: a retrospective analysis from the PETACC 3 study

A recent meta-analysis showed that in people with type 1 or type 2 diabetes, DSNS were associated with reduced: 3 HbA1c post-prandial glucose levels incremental glucose response mean blood glucose glucose variability mean administered insulin dose

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Structural Significance of Non-Proteinogenic Residues: Aib (N-terminal position):Reduces conformational flexibility of the peptide backbone, locking it into a bioactive conformation and enhancing its stability against enzymatic degradation D-2-Naphthylalanine (position 3):Provides hydrophobic interactions with the GHSR-1a receptor binding pocket while conferring resistance to peptidase cleavage