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PKA phosphorylates multiple targets involved in intracellular Ca 2+ homeostasis, such as K ATP channels that control membrane depolarisation (Gromada et al., 1997) and inositol triphosphate receptors that promote release of Ca 2+ from intracellular stores (Tsuboi et al., 2003)

This systematic approach ensures you never inject into the same millimeter-square tissue twice within 4 to 6 weeks

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