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Ferroportin (FPN), the only known cellular iron efflux protein, directly reduces intracellular iron levels to inhibit ferroptosis ( 2 , functions as a radical-trapping antioxidant (RTA) that neutralizes lipid peroxyl radicals

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31 Elevated levels of 3-NT have been described in a number of diseases with an oxidative stress pathology, including alcoholism, smoking, diabetes, atherosclerosis and cystic fibrosis