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Os benefcios mais bem documentados nos estudos pr-clnicos incluem: acelerao da cicatrizao de tendes e ligamentos (com melhora das propriedades biomecnicas), proteo da mucosa gstrica contra AINEs e lcool (reduo de 78% da superfcie ulcerosa em modelos animais), estimulao da angiognese via VEGF, e efeitos neuroprotetores em modelos de leso cerebral

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They operate through fundamentally different biological pathways, which is why comparing them purely on "wrinkle outcomes" misses most of the picture

Published literature reports doses of 12 mg/kg for in vivo research