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Clinical Appropriateness vs

By #Type: GLP-1 Receptor Agonists (Next-Gen) Dual Agonists (GLP-1 + GIP) Triple Agonists (GLP-1 + GIP + Glucagon) Amylin-Based Combination Therapies By #Application: Chronic Weight Management Type 2 Diabetes & Obesity Treatment Cardiometabolic Disorder Management Obesity-Related Liver Disease (NASH/MASH) Definition: Next-Generation Obesity Drug Pipeline refers to the portfolio of advanced pharmacological therapies under clinical development aimed at treating obesity through multi-target metabolic pathways

Further evaluation of metabolic models of the microbiota by examining 70 metabolic pathways from the KEGG database revealed a significant increase in the function of glutamate-cysteine ligase and GSH biosynthesis in the metformin-modulated microbiota (Fig

34 , 11041120.e1108 (2022)